Peripheral blood neutrophil rheology measured by micropore filtration reflects Behçet's disease activity well

S Iijima, F Otsuka - Journal of dermatological science, 1997 - Elsevier
Activated neutrophils take a long time to pass through a narrow lumen like a micropore, and
are supposed to play a deteriorating effect on microcirculation. Although the activation of
neutrophils has been demonstrated in Behçet's disease, nobody analyzes the clinical
activity of the disease by means of the rheological measure of neutrophils activity. Using a
micropore (pore diameter 5 μm) filtration technique, we measured the filtration time of
peripheral blood neutrophils, as a rheological measure of their activity, in order to determine …
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